Shi Ningcuo TEMPULINE is a brand under Beijing Jingyu Yimei Biotechnology Co., Ltd. Yimei Technology has a strong background in research and technology. In July 2023, as the leading unit, it jointly with the Institute of Physics and Chemistry of the Chinese Academy of Sciences, the Qingdao Institute of Energy Research of the Chinese Academy of Sciences, Qingdao University of Science and Technology, Jingyu Furui Group, and Peking University First Hospital, etc., jointly applied for the "Medical Poly-Lactic Acid Derivatives" project and was selected. It undertook the task of researching and developing the import substitution of this material and was included in the "Bio-Medical Materials Innovation Task Bidding and Commanding (First Batch) List of Invited Bidders" released by the Ministry of Industry and Information Technology. 

Shi Ningcuo has obtained the 13th domestic license for anti-aging injections for children. The brand has chosen the highly trusted blue color as its brand color and adopted the inverted T symbol as its brand identification symbol. While emphasizing the technological aspect, it also does not forget to convey to consumers a luxurious and high-end usage experience.

时凝萃TEMPULINE是北京京宇一美生物科技有限责任公司旗下品牌，一美科技研发与技术背景雄厚，在2023年7月作为牵头单位，联合中科院理化所、中科院青岛能源所、青岛科技大学、京宇复瑞集团、北京大学第一医院等单位，共同申报的“医用聚乳酸衍生物”项目入选，承担该材料进口替代的攻关任务，入选工业和信息化部发布的《生物医用材料创新任务揭榜挂帅（第一批）入围揭榜单位名单》。

时凝萃获批国内第13款童颜针牌照，品牌选用高信任感的蓝色作为品牌色，选用倒映T作为品牌识别符号，强调科技感的同时也不忘传达给消费者轻奢高级的使用体验。